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[TileDB::Buffer] Error: Cannot read from buffer; End of buffer reached.

时间:2024-02-16 12:23:30浏览次数:43  
标签:调用 End 染色体 buffer zlib Buffer 报错

 

001、问题:

 gatk DBI 模块在 sheep 1号染色体(其他染色体同样的命令并没有报错;一共134 sheep个体)调用GenotypeGVCFs 命令call  snps时出现如下报错:

 

002、问题原因

it looks like we are hitting the limits of zlib memory-wise. (达到zlib库的内存上限?)

 

003、解决方法

绵羊的1号染色体最长,将染色体打断,分成多个段去调用GenomicsDBImport 建库,然后再调用GenotypeGVCFs call SNPs, 比如分成三段,测试效果如下:

 

 

 

reference:

01:https://github.com/broadinstitute/gatk/issues/7012

 

标签:调用,End,染色体,buffer,zlib,Buffer,报错
From: https://www.cnblogs.com/liujiaxin2018/p/18017033

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