drug

2024-11-11visualvm远程连接Docker容器中部署的java应用并监控
visualvm远程连接Docker容器中部署的java应用前言jdk1.8中自带了，java11中需要单独下载下载地址visualvm下载地址简介java虚拟机监控，故障排查及性能分析工具。网络配置局域网与docker内网打通，请参考：办公网络与Docker内网网络互通服务于网络服务名称节点IPj
2024-06-02创建医疗知识图谱：导入数据
将的代码修改成这样：#!/usr/bin/envpython3#coding:utf-8#File:MedicalGraph.py#Author:lhy<[email protected],https://huangyong.github.io>#Date:18-10-3#-*-coding:utf-8-*-importosimportjsonfrompy2neoimportGraph,NodeclassMedicalGr
2023-12-18Predicting Drug-Target Interactions. drug-target interactions prediction
2023[j22]JunjunZhang, MinzhuXie:Graphregularizednon-negativematrixfactorizationwithL2,1 normregularizationtermsfordrug-targetinteractionsprediction. BMCBioinform. 24(1): 375 (2023)2022[j21]JunjunZhan
2023-12-08Graph regularized non-negative matrix factorization with prior knowledge consistency constraint for
Graphregularizednon-negativematrixfactorizationwithpriorknowledgeconsistencyconstraintfordrug-targetinteractionspredictionJunjunZhang 1, MinzhuXie 2 3Affiliations expandPMID: 36581822 PMCID: PMC9798666 DOI: 10.1186/s1285
2023-12-08Drug response prediction using graph representation learning and Laplacian feature selection
DrugresponsepredictionusinggraphrepresentationlearningandLaplacianfeatureselectionMinzhuXie 1 2, XiaowenLei 3, JianchenZhong 3, JianxingOuyang 3, GuijingLi 3Affiliations expandPMID: 36494630 PMCID: PMC9733001 DOI:
2023-12-08Graph regularized non-negative matrix factorization with [Formula: see text] norm regularization ter
Graphregularizednon-negativematrixfactorizationwith[Formula:seetext]normregularizationtermsfordrug-targetinteractionspredictionJunjunZhang 1, MinzhuXie 2 3Affiliations expandPMID: 37789278 PMCID: PMC10548602 DOI: 10.11
2023-06-21What are the differences between in vivo and in vitro testing of drugs for toxicology Studies?
Intoxicologystudies,therearetwomaintypesoftestsusedtoassessthesafetyandpotentialtoxiceffectsofdrugs:invivotestsandinvitrotests.Weknowthatthetraditionalmethodofdrugtoxicologyresearchistouseanimalmodelsforinvivo
2023-06-14An analysis of what are the drug targets for the treatment of systemic lupus erythematosus
Systemiclupuserythematosus(SLE)isanautoimmunediseasethatproduceslargeamountsofimmunecomplexesandautoantibodiesandcausesdamagetothekidneys,skin,joints,andcentralnervoussystem.CurrentSLEtreatmentismostlyglucocorticoid-ledd
2023-05-30The Importance of Particle Size Analysis in Preformulation Studies
Thesizeoftheparticlesiscalledparticlesize.TheparticlesizeoftheAPIiscloselyrelatedtothehomogeneityofthepreparationprocessintermsofmixing,theaccuracyofdosage,andcompressibility,andithasanimpactonthesolubility,durat
2023-05-18How to accelerate the process of preclinical studies of new medicines
Accordingtothedrugdevelopmentprocess,newdrugdevelopmentcanbedividedintopreclinicalandclinicalstudies.Theformeristhesumofalltheresearchworkdoneonadrugbeforeitentersclinicaltrials,andthelatteristheresearchworkdone
2023-05-10Understanding Preclinical Research: The Key to Successful Innovative Drug Development
Thefirstchallengeindrugdevelopmentispreclinicalresearchofnewdrugs,whichreferstochemicalsynthesisornaturalproductpurificationstudies,druganalysisstudies,pharmacodynamics,pharmacokinetics,toxicology,andpharmacologystudiesperfo
2023-05-08Exploring the Use of Humanized Mouse Models in Drug Safety Evaluation
Thepurposeofdrugdevelopmentistofindnewsafe,effectivedrugsofhighqualityandstabilitytocurediseasesandsavelives.Developinganewdrugisaverycomplexprocess,butitcanbedividedinto preclinicalresearch andclinicalstudiesofa
2023-04-04The role of local toxicity testing in evaluating new drugs
Aseriesoftoxicitystudiesarerequiredtorevealthepossibletoxicreactionsofdrugsbeforeclinicalapplicationandtoensurethesafetyandeffectivenessofclinicaluse.Localtoxicitytestisanintegralpartoftoxicologyresearch,whichisdesi
2023-03-25C# 操作 MySql
C#操作MySql简介代码介绍代码实现创建数据库创建数据表查询数据事务代码示例简介工作中大多数情况下用的都是MySql但一直没有记录，相关操作。这篇文章以便MySql.Data库
2023-03-21oracle使用存储过程返回游标实现报表查询
最近在oracle中通过存储过程实现一个报表查询，查询涉及到数据计算这里使用了临时表和存储过程实现输出查询，java接受游标变量返回结果集第一步、创建统计使用的临时表CREA
2023-02-07解决“ORA-00937: 不是单组分组函数”报错
原SQL：selectdistincta.begin_exec_time,b.drug_code,b.drug_name,b.drug_spec,sum(b.public_retail_price*a.total_drug)as"总金额",b.public_retail_pricefromZOE
2022-10-05【图神经网络DGL】数据封装和栗子
学习总结（1）DGL中数据的封装。（2）基于MessagePassing机制实现图神经网络。文章目录学习总结一、DGL简介和安装二、基础教程三、图3.1创