AP1867
CAS:195514-23-9
品牌:MedChemExpress (MCE)
存储条件:Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性:AP1867 是一种合成的 FKBP12F36V 定向配体[1]。 IC50 和目标:FKBP[1]
体外:AP1867 与野生型 FKBP (Kd = 67 nM)[2] 结合。
参考文献:
[1]. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.
[2]. Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408. 详情:https://www.medchemexpress.cn/AP1867.html