nginx 报错 upstream timed out (110: Connection timed out)

upstream timed out (110: Connection timed out) while reading response header from upstream,

在http下面加：　　

    proxy_http_version 1.1;
    proxy_set_header Connection "";
    large_client_header_buffers 4 16k;
    client_max_body_size 500m;
    client_body_buffer_size 128k;
    fastcgi_connect_timeout 300;
    fastcgi_read_timeout 300;
    fastcgi_send_timeout 300;
    fastcgi_buffer_size 64k;
    fastcgi_buffers 4 32k;
    fastcgi_busy_buffers_size 64k;
    fastcgi_temp_file_write_size 64k;